Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.40 |
| ▸ | BRSK1 | Q8TDC3 | 1/20 | 0.40 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20837285 | 0.83 | LMNA (0.47) | ALDH1A1LMNACDK5DYRK1AMAPK1 | |
| SCHEMBL20837304 | 0.81 | KMT2A (0.45) | ALDH1A1LMNACDK5DYRK1AMAPK1 | |
| SCHEMBL20837277 | 0.71 | PTGDR2 (0.44) | CDK5DYRK1AMAPK1NPSR1RPS6KA5 | |
| SCHEMBL12464662 | 0.71 | RPS6KA3 (0.49) | ALDH1A1LMNACDK5DYRK1AMAPK1 | |
| SCHEMBL10166769 | 0.70 | MAPK1 (0.68) | ALDH1A1LMNACDK5DYRK1AMAPK1 | |
| SCHEMBL20837070 | 0.69 | MAPK1 (0.43) | ALDH1A1LMNACDK5DYRK1AMAPK1 | |
| SCHEMBL11485891 | 0.69 | KDM4E (0.71) | ALDH1A1LMNACDK2KMT2ANFKB1 | |
| SCHEMBL571266 | 0.69 | ALDH1A1 (0.46) | ALDH1A1LMNAAKT2SMN1; SMN2GAA | |
| SCHEMBL19926065 | 0.69 | GSK3A (0.57) | ALDH1A1LMNACDK5DYRK1AMAPK1 | |
| SCHEMBL1057636 | 0.67 | AKT2 (0.66) | ALDH1A1LMNACDK5DYRK1AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101583276-A | Substituted 1- (3-pyridyl) -pyrazol-4-yl acetic acids, method for the production thereof, and use thereof as herbicides and plant growth regulators | BAYER CROPSCIENCE AG (DE) | 2009-11-18 | — | — | CN | disclosed |