SCHEMBL571266

SCHEMBL571266

O=C(OCl)c1n[nH]c(Cl)c1-c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
LMNA P02545 3/20 0.46
TYMP P19971 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
HTT P42858 1/20 0.37
GAA P10253 1/20 0.37
PTGS1 P23219 1/20 0.36
KDM4E B2RXH2 2/20 0.36
STAT3 P40763 1/20 0.36
HIF1A Q16665 1/20 0.36
MAP2 P11137 2/20 0.35
ADORA3 P0DMS8 1/20 0.35
ADORA2A P29274 1/20 0.35
HPGD P15428 2/20 0.35
CYP1A2 P05177 1/20 0.35
XBP1 P17861 1/20 0.35
CYP2C19 P33261 1/20 0.35
TP53 P04637 1/20 0.35
CHEK1 O14757 1/20 0.34
AKT2 P31751 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27764468 0.69 ALDH1A1 (0.46) ALDH1A1LMNASMN1; SMN2GAAKDM4E
SCHEMBL16260565 0.67 KDM4E (0.57) ALDH1A1LMNASMN1; SMN2GAAKDM4E
SCHEMBL3435970 0.66 LMNA (0.43) ALDH1A1LMNASMN1; SMN2GAAPTGS1
SCHEMBL7402340 0.66 LMNA (0.70) ALDH1A1LMNASMN1; SMN2GAAKDM4E
SCHEMBL15272525 0.65 LMNA (0.49) ALDH1A1LMNASMN1; SMN2HTTGAA
Bicarbonate SCHEMBL166149 0.65 HPGD (0.50) ALDH1A1LMNASMN1; SMN2GAAPTGS1
SCHEMBL7403288 0.65 LMNA (0.49) ALDH1A1LMNASMN1; SMN2KDM4ECYP1A2
SCHEMBL5188872 0.65 TYMP (0.41) ALDH1A1LMNATYMPSMN1; SMN2KDM4E
SCHEMBL20837285 0.64 LMNA (0.47) ALDH1A1LMNASMN1; SMN2KDM4ECYP1A2
SCHEMBL27455057 0.64 LMNA (0.47) ALDH1A1LMNASMN1; SMN2KDM4ECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1200 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113367128-A Composition containing R-type oxadiazolyl aryl formamide compound and safener and application thereof 江苏清原农冠杂草防治有限公司 2021-09-10 CN claimed
CN-105028414-A HERBICIDE-SAFENER COMBINATION BAYER IP GMBH 2015-11-11 CN claimed
US-20130130899-A1 HERBICIDAL COMPOSITIONS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-05-23 US claimed
CN-102300459-A Herbicide-safener combination 2011-12-28 CN claimed
CN-102227165-A Herbicide/safener combination BAYER CROPSCIENCE AG 2011-10-26 CN claimed
CN-102227162-A Herbicide-safener combination BAYER CROPSCIENCE AG 2011-10-26 CN claimed
CN-102223795-A Herbicide-safener combination BAYER CROPSCIENCE AG 2011-10-19 CN claimed
CN-101785473-A Safening method BAYER CROPSCIENCE GMBH 2010-07-28 CN claimed
US-20100137139-A1 HERBICIDE/SAFENER COMBINATION BAYER CROPSCIENCE AG (DE) 2010-06-03 US claimed
US-20100137138-A1 HERBICIDE/SAFENER COMBINATION BAYER CROPSCIENCE AG (DE) 2010-06-03 US claimed
US-20100137137-A1 HERBICIDE/SAFENER COMBINATION BAYER CROPSCIENCE AG (DE) 2010-06-03 US claimed
EP-1104232-B2 HERBICIDES BAYER CROPSCIENCE AG (DE) 2010-03-17 EP claimed
CN-1988801-A security method BAYER CROPSCIENCE GMBH (DE) 2007-06-27 CN claimed
EP-1791425-A2 SAFENING METHOD Bayer CropScience AG (DE) 2007-06-06 EP claimed
US-20070021303-A1 Safening method BAYER CROPSCIENCE AG (DE) 2007-01-25 US claimed
WO-2006007982-A2 SAFENING METHOD BAYER CROPSCIENCE GMBH (DE) 2006-01-26 WO claimed
EP-1104232-B1 HERBICIDES BAYER CROPSCIENCE GMBH (DE) 2005-05-04 EP claimed
US-20030069138-A1 Synergistic herbicidal mixture of a). a heteroaryloxy- or aryloxy-phenoxypropionic acid, or salt or ester and b). one or more herbicides that are selective in rice BAYER INTELLECTUAL PROPERTY GMBH (DE) 2003-04-10 US claimed
US-20020123428-A1 Can be used against harmful plants in crops, preferably in rice AVENTIS CROPSCIENCE GMBH (DE) 2002-09-05 US claimed
CN-1309533-A Herbicidal composition AVENTIS CORPSCIENCE GMBH (DE) 2001-08-22 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100137138-A1 HERBICIDE/SAFENER COMBINATION DDT, GSTO1, GAP43 ALDH1A1 226/4885LMNA 3655/4885TYMP 1381/4885
US-20070021303-A1 Safening method BCL2, BCL2L11, CYP51A1 ALDH1A1 640/4885LMNA 815/4885TYMP 2666/4885
US-20100137137-A1 HERBICIDE/SAFENER COMBINATION DDT, CYP2W1, GAP43 ALDH1A1 209/4885LMNA 4155/4885TYMP 1200/4885
US-20100137139-A1 HERBICIDE/SAFENER COMBINATION CYP2W1, DDT, CBR3 ALDH1A1 551/4885LMNA 2737/4885TYMP 3448/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.