Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | BPTF | Q12830 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL423972 | 0.81 | — | — | |
| SCHEMBL429744 | 0.79 | ATM (0.56) | ATMALDH1A1SMN1; SMN2BPTFPOLB | |
| SCHEMBL9040661 | 0.79 | ATM (0.56) | ATMALDH1A1SMN1; SMN2BPTFPOLB | |
| SCHEMBL11406639 | 0.76 | — | — | |
| SCHEMBL27765152 | 0.73 | POLB (0.51) | ALDH1A1SMN1; SMN2POLBTDP1KMT2A | |
| SCHEMBL8642977 | 0.71 | — | — | |
| SCHEMBL10972781 | 0.71 | ALDH1A1 (0.50) | ATMALDH1A1SMN1; SMN2BPTFPOLB | |
| SCHEMBL12667884 | 0.67 | SMN1; SMN2 (0.44) | ATMALDH1A1SMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL3082371 | 0.66 | ATM (0.52) | ATMALDH1A1SMN1; SMN2BPTFL3MBTL1 | |
| SCHEMBL6203722 | 0.66 | ATM (0.52) | ATMALDH1A1SMN1; SMN2BPTFL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101395131-B | Method for producing aminoacetylpyrrolidinecarbonitrile derivative and production intermediate thereof | KYORIN SEIYAKU KK | 2012-11-14 | — | — | CN | disclosed |
| CN-101395131-A | Method for producing aminoacetylpyrrolidinecarbonitrile derivative and production intermediate thereof | KYORIN SEIYAKU KK (JP) | 2009-03-25 | — | — | CN | disclosed |