Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27613187 | 0.86 | F10 (0.40) | L3MBTL1CYP3A4ALDH1A1TSHRCYP2C19 | |
| SCHEMBL9833387 | 0.85 | ALDH1A1 (0.41) | ALDH1A1KLK5 | |
| SCHEMBL27765204 | 0.80 | MAPT (0.40) | MAPTSMN1; SMN2PKML3MBTL1CYP3A4 | |
| SCHEMBL27892297 | 0.78 | AAK1 (0.36) | SMN1; SMN2PKML3MBTL1CYP3A4NPSR1 | |
| SCHEMBL27660598 | 0.77 | ATM (0.38) | MAPTL3MBTL1NPSR1ALDH1A1 | |
| SCHEMBL8069348 | 0.75 | ALDH1A1 (0.40) | MAPTCYP3A4NPSR1ALDH1A1 | |
| SCHEMBL28301558 | 0.75 | ADRA2A (0.40) | MAPTL3MBTL1NPSR1ALDH1A1 | |
| SCHEMBL5650824 | 0.74 | ATM (0.38) | L3MBTL1 | |
| SCHEMBL5652634 | 0.74 | ATM (0.38) | L3MBTL1 | |
| SCHEMBL4941845 | 0.74 | SMN1; SMN2 (0.48) | MAPTSMN1; SMN2PKMCYP3A4NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101589056-A | Depsipeptide and therepic use thereof | UNIV SOUTHAMPTON (GB) | 2009-11-25 | — | — | CN | disclosed |