Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK8 | P49336 | 4/20 | 0.35 |
| ▸ | GCK | P35557 | 3/20 | 0.35 |
| ▸ | FAAH | O00519 | 4/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727414 | 0.96 | CDK8 (0.36) | CDK8GCKFAAHATMTDP1 | |
| SCHEMBL27724978 | 0.83 | ATM (0.36) | CDK8GCKFAAHATMTDP1 | |
| SCHEMBL3556176 | 0.82 | MAOA (0.45) | GCKFAAHATMTDP1L3MBTL1 | |
| SCHEMBL28012733 | 0.79 | MAPK14 (0.37) | GCKMAPK14BRAF | |
| SCHEMBL3552349 | 0.78 | MET (0.40) | GCKBRAF | |
| SCHEMBL12280370 | 0.76 | CYP1A2 (0.36) | GCKATMTDP1L3MBTL1EGFR | |
| SCHEMBL3615623 | 0.75 | MET (0.51) | MAPK14EGFR | |
| SCHEMBL6038491 | 0.74 | L3MBTL1 (0.41) | ATMTDP1L3MBTL1 | |
| SCHEMBL6038760 | 0.74 | GCK (0.39) | GCKBRAF | |
| SCHEMBL1726338 | 0.74 | NPC1 (0.44) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101454311-B | Salt of phenoxypyridine derivative, crystal thereof and process for producing the same | EISAI R&D MAN CO LTD | 2013-03-27 | — | — | CN | disclosed |
| CN-101454311-A | Salt of phenoxypyridine derivative, crystal thereof and process for producing the same | EISAI R&D MAN CO LTD (JP) | 2009-06-10 | — | — | CN | disclosed |