Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | GRM4 | Q14833 | 7/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14342571 | 0.81 | PTGS2 (0.68) | KDM4EHPGDLMNACYP1A2ALDH1A1 | |
| SCHEMBL17068289 | 0.75 | PTGS2 (0.56) | KDM4EHPGDLMNACYP1A2ALDH1A1 | |
| SCHEMBL1793302 | 0.73 | PTGS2 (0.87) | KDM4EHPGDLMNACYP1A2ALDH1A1 | |
| SCHEMBL1793300 | 0.73 | PTGS2 (0.87) | KDM4EHPGDLMNACYP1A2ALDH1A1 | |
| SCHEMBL28949611 | 0.73 | KDM4E (0.57) | KDM4EHPGDLMNACYP1A2ALDH1A1 | |
| SCHEMBL14342572 | 0.73 | PTGS2 (0.87) | KDM4EHPGDLMNACYP1A2ALDH1A1 | |
| SCHEMBL1793303 | 0.73 | PTGS2 (0.87) | KDM4EHPGDLMNACYP1A2ALDH1A1 | |
| SCHEMBL27773488 | 0.72 | POLB (0.50) | KDM4EHPGDLMNACYP1A2ALDH1A1 | |
| SCHEMBL29472997 | 0.70 | MEN1 (0.64) | KDM4EHPGDLMNACYP1A2ALDH1A1 | |
| SCHEMBL11374609 | 0.70 | KDM4E (1.00) | KDM4EHPGDLMNAALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101611014-B | Amidopyrazoles as FGFR inhibitors | ASTRAZENECA AB | 2012-05-30 | — | — | CN | disclosed |
| CN-101611014-A | Amidopyrazoles as FGFR inhibitors | ASTRAZENECA AB (SE) | 2009-12-23 | — | — | CN | disclosed |