Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | HNF4A | P41235 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | DPYD | Q12882 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16228971 | 0.84 | PTGS2 (0.50) | KDM4EHPGDLMNACYP1A2PTGS2 | |
| SCHEMBL16228972 | 0.84 | PTGS2 (0.50) | KDM4EHPGDLMNACYP1A2PTGS2 | |
| SCHEMBL28049926 | 0.78 | PTGS2 (0.43) | KDM4EHPGDLMNACYP1A2PTGS2 | |
| SCHEMBL28825766 | 0.78 | PTGS2 (0.43) | KDM4EHPGDLMNACYP1A2PTGS2 | |
| SCHEMBL28050047 | 0.78 | DAO (0.43) | KDM4EHPGDLMNACYP1A2PTGS2 | |
| SCHEMBL14342571 | 0.75 | PTGS2 (0.68) | KDM4EHPGDLMNACYP1A2PTGS2 | |
| SCHEMBL1793303 | 0.74 | PTGS2 (0.87) | KDM4EHPGDLMNACYP1A2PTGS2 | |
| SCHEMBL14342572 | 0.74 | PTGS2 (0.87) | KDM4EHPGDLMNACYP1A2PTGS2 | |
| SCHEMBL1793302 | 0.74 | PTGS2 (0.87) | KDM4EHPGDLMNACYP1A2PTGS2 | |
| SCHEMBL1793300 | 0.74 | PTGS2 (0.87) | KDM4EHPGDLMNACYP1A2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103748079-B | Pyridazinone mixture and the purposes as DAAO inhibitor thereof | TAKEDA PHARMACEUTICAL CO.,LTD. (JP) | 2016-03-16 | — | — | CN | disclosed |