Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 5/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.45 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14488046 | 0.89 | PKM (0.66) | PKMPOLBHTTPIK3CASMN1; SMN2 | |
| SCHEMBL27838815 | 0.83 | PIK3CA (0.54) | PKMHTTPIK3CASMN1; SMN2LMNA | |
| SCHEMBL27788926 | 0.82 | PIK3CA (0.55) | PKMPOLBHTTPIK3CASMN1; SMN2 | |
| SCHEMBL27819109 | 0.79 | PIK3CA (0.66) | PKMPOLBHTTPIK3CASMN1; SMN2 | |
| SCHEMBL27840965 | 0.77 | PIK3CA (0.76) | PKMPOLBHTTPIK3CASMN1; SMN2 | |
| SCHEMBL2302263 | 0.76 | RXFP1 (0.75) | POLBHTTPIK3CASMN1; SMN2MEN1 | |
| SCHEMBL27858470 | 0.74 | PIK3CA (0.77) | PKMPOLBHTTPIK3CASMN1; SMN2 | |
| SCHEMBL27838810 | 0.73 | PIK3CA (1.00) | PKMPOLBHTTPIK3CASMN1; SMN2 | |
| SCHEMBL28795786 | 0.73 | PIK3CA (0.69) | PKMPOLBHTTPIK3CASMN1; SMN2 | |
| SCHEMBL27858464 | 0.73 | PIK3CA (0.69) | PKMPOLBHTTPIK3CASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101602737-B | Benzenesulfonyl quinoxaline compound and preparation method and application thereof | UNIV ZHEJIANG | 2011-09-14 | — | — | CN | disclosed |
| CN-101602737-A | Benzenesulfonyl quinoxaline compound and preparation method and purposes | UNIV ZHEJIANG (CN) | 2009-12-16 | — | — | CN | disclosed |