Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27788926 | 0.86 | PIK3CA (0.55) | PIK3CAL3MBTL1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL27767403 | 0.83 | PKM (0.58) | PIK3CAL3MBTL1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL27819107 | 0.77 | PIK3CA (0.54) | PIK3CAKMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL28246863 | 0.76 | KDM4E (0.61) | PIK3CAL3MBTL1KMT2AMEN1HTT | |
| SCHEMBL27843384 | 0.76 | L3MBTL1 (0.47) | PIK3CAL3MBTL1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL16077775 | 0.75 | TDP1 (0.54) | L3MBTL1KMT2AMEN1SMN1; SMN2HTT | |
| SCHEMBL3694105 | 0.74 | TDP1 (0.52) | PIK3CAL3MBTL1KMT2AMEN1ATM | |
| Potassium Ion SCHEMBL3703885 | 0.74 | TDP1 (0.52) | PIK3CAL3MBTL1KMT2AMEN1ATM | |
| Lithium Ion SCHEMBL3694518 | 0.74 | TDP1 (0.52) | PIK3CAL3MBTL1KMT2AMEN1ATM | |
| SCHEMBL2302031 | 0.74 | ALDH1A1 (0.78) | PIK3CAL3MBTL1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102250022-B | Substituted quinoxalinamine compounds, and preparation method and application thereof | UNIV ZHEJIANG | 2013-10-16 | — | — | CN | disclosed |
| CN-102250022-A | Substituted quinoxalinamine compounds, and preparation method and application thereof | UNIV ZHEJIANG | 2011-11-23 | — | — | CN | disclosed |
| CN-101602737-B | Benzenesulfonyl quinoxaline compound and preparation method and application thereof | UNIV ZHEJIANG | 2011-09-14 | — | — | CN | disclosed |