Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27838815 | 0.86 | PIK3CA (0.54) | PIK3CAKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL27767403 | 0.82 | PKM (0.58) | PIK3CAKDM4ENPSR1RXFP1KMT2A | |
| SCHEMBL27843384 | 0.81 | L3MBTL1 (0.47) | PIK3CAKDM4ENPSR1RXFP1KMT2A | |
| SCHEMBL16077775 | 0.77 | TDP1 (0.54) | KDM4ENPSR1RXFP1KMT2AMEN1 | |
| SCHEMBL3697579 | 0.77 | TDP1 (0.54) | KDM4ENPSR1RXFP1KMT2AMEN1 | |
| SCHEMBL29714271 | 0.77 | TDP1 (0.54) | KDM4ENPSR1RXFP1KMT2AMEN1 | |
| SCHEMBL61762 | 0.77 | TDP1 (0.54) | KDM4ENPSR1RXFP1KMT2AMEN1 | |
| SCHEMBL3694109 | 0.76 | TDP1 (0.52) | KDM4ENPSR1RXFP1KMT2AMEN1 | |
| Potassium Ion SCHEMBL3703885 | 0.76 | TDP1 (0.52) | PIK3CAKDM4ENPSR1RXFP1KMT2A | |
| SCHEMBL3694520 | 0.76 | TDP1 (0.52) | KDM4ENPSR1RXFP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102250022-B | Substituted quinoxalinamine compounds, and preparation method and application thereof | UNIV ZHEJIANG | 2013-10-16 | — | — | CN | disclosed |
| CN-102250022-A | Substituted quinoxalinamine compounds, and preparation method and application thereof | UNIV ZHEJIANG | 2011-11-23 | — | — | CN | disclosed |
| CN-101602737-B | Benzenesulfonyl quinoxaline compound and preparation method and application thereof | UNIV ZHEJIANG | 2011-09-14 | — | — | CN | disclosed |
| CN-101602737-B | Benzenesulfonyl quinoxaline compound and preparation method and application thereof | UNIV ZHEJIANG | 2011-09-14 | — | — | CN | disclosed |
| CN-101602737-A | Benzenesulfonyl quinoxaline compound and preparation method and purposes | UNIV ZHEJIANG (CN) | 2009-12-16 | — | — | CN | disclosed |