Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 10/20 | 0.44 |
| ▸ | MTOR | P42345 | 5/20 | 0.44 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | RICTOR | Q6R327 | 1/20 | 0.41 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.41 |
| ▸ | MAPKAP1 | Q9BPZ7 | 1/20 | 0.41 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.40 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.40 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL369829 | 0.82 | TP53 (0.49) | TP53PIK3CAPIK3CDPIK3CBPIM1 | |
| SCHEMBL18704848 | 0.78 | TP53 (0.50) | TP53PIK3CAPIK3CDPIK3CBPIM1 | |
| SCHEMBL4480117 | 0.72 | TP53 (0.50) | TP53PIK3CAMTORPIK3R1DHFR | |
| SCHEMBL4283927 | 0.71 | ALDH1A1 (0.42) | ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL21358271 | 0.68 | DHFR (0.74) | PIK3CAMTORPIK3R1DHFRRICTOR | |
| SCHEMBL237122 | 0.68 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL31561546 | 0.68 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL6239333 | 0.68 | TP53 (0.64) | TP53PIK3CAMTORPIK3R1PIK3CD | |
| SCHEMBL7015249 | 0.68 | TP53 (0.60) | TP53PIK3CAPIK3CBPIM1ALDH1A1 | |
| SCHEMBL25251956 | 0.67 | BCHE (0.46) | TP53KMT2AMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790877-B2 | Antisense oligonucleotides with increased RNase sensitivity | GEN-PROBE, INCORPORATED (US) | 2010-09-07 | — | — | US | disclosed |
| EP-1171634-B1 | AMPLIFICATION AND SEQUENCING PRIMER PAIRS AND USE THEREOF | GEN PROBE INC (US) | 2005-10-26 | — | — | EP | disclosed |
| EP-1019539-A4 | COMBINATORIAL ANTISENSE LIBRARY | GEN PROBE INC (US) | 2005-03-09 | — | — | EP | disclosed |
| US-20040014129-A1 | Amplification primer pairs and use thereof | GEN-PROBE INCORPORATED | 2004-01-22 | — | — | US | disclosed |
| US-20030045488-A1 | Antisense oligonucleotides comprising universal and/or degenerate bases | OASIS BIOSCIENCES INCORPORATED | 2003-03-06 | — | — | US | disclosed |
| US-20020119533-A1 | Amplification primer pairs and use thereof | OASIS BIOSCIENCES INCORPORATED | 2002-08-29 | — | — | US | disclosed |
| EP-1171634-A4 | AMPLIFICATION AND SEQUENCING PRIMER PAIRS AND USE THEREOF | OASIS BIOSCIENCES INC (US) | 2002-07-31 | — | — | EP | disclosed |
| EP-1171634-A1 | AMPLIFICATION AND SEQUENCING PRIMER PAIRS AND USE THEREOF | Oasis Biosciences, Inc. (US) | 2002-01-16 | — | — | EP | disclosed |
| WO-2000061807-A1 | AMPLIFICATION AND SEQUENCING PRIMER PAIRS AND USE THEREOF | OASIS BIOSCIENCES, INC. (US) | 2000-10-19 | — | — | WO | disclosed |
| EP-1019539-A1 | COMBINATORIAL ANTISENSE LIBRARY | Oasis Biosciences, Inc. (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1999018238-A1 | COMBINATORIAL ANTISENSE LIBRARY | OASIS BIOSCIENCES, INC. (US) | 1999-04-15 | — | — | WO | disclosed |