Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 17/20 | 0.39 |
| ▸ | MTOR | P42345 | 9/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 5/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | RICTOR | Q6R327 | 1/20 | 0.36 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.36 |
| ▸ | MAPKAP1 | Q9BPZ7 | 1/20 | 0.36 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.36 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.36 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5004595 | 0.75 | FDPS (0.35) | PIK3CBALDH1A1CYP1A2HDAC6 | |
| SCHEMBL9014630 | 0.70 | FDPS (0.36) | USP2ALDH1A1CYP1A2HSD17B10HDAC6 | |
| SCHEMBL28480707 | 0.69 | CDK1 (0.47) | PIK3CGALDH1A1HSD17B10HDAC6 | |
| SCHEMBL5430808 | 0.68 | HDAC6 (0.34) | PI4KBALDH1A1HSD17B10HDAC6 | |
| SCHEMBL27303515 | 0.68 | HDAC6 (0.40) | ALDH1A1HSD17B10HDAC6 | |
| SCHEMBL28384782 | 0.67 | KDM4E (0.40) | PIK3CAMTORRICTORRPTORMAPKAP1 | |
| SCHEMBL3506547 | 0.67 | ADORA2A (0.46) | PI4KB | |
| SCHEMBL5034216 | 0.66 | HDAC6 (0.40) | ALDH1A1HSD17B10HDAC6 | |
| SCHEMBL3144585 | 0.66 | HDAC6 (0.40) | ALDH1A1HSD17B10HDAC6 | |
| SCHEMBL27944268 | 0.66 | HSP90AA1 (0.41) | ALDH1A1HSD17B10HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790877-B2 | Antisense oligonucleotides with increased RNase sensitivity | GEN-PROBE, INCORPORATED (US) | 2010-09-07 | — | — | US | disclosed |
| EP-1171634-B1 | AMPLIFICATION AND SEQUENCING PRIMER PAIRS AND USE THEREOF | GEN PROBE INC (US) | 2005-10-26 | — | — | EP | disclosed |
| EP-1019539-A4 | COMBINATORIAL ANTISENSE LIBRARY | GEN PROBE INC (US) | 2005-03-09 | — | — | EP | disclosed |
| US-20040014129-A1 | Amplification primer pairs and use thereof | GEN-PROBE INCORPORATED | 2004-01-22 | — | — | US | disclosed |
| US-20030045488-A1 | Antisense oligonucleotides comprising universal and/or degenerate bases | OASIS BIOSCIENCES INCORPORATED | 2003-03-06 | — | — | US | disclosed |
| US-20020119533-A1 | Amplification primer pairs and use thereof | OASIS BIOSCIENCES INCORPORATED | 2002-08-29 | — | — | US | disclosed |
| EP-1171634-A4 | AMPLIFICATION AND SEQUENCING PRIMER PAIRS AND USE THEREOF | OASIS BIOSCIENCES INC (US) | 2002-07-31 | — | — | EP | disclosed |
| EP-1171634-A1 | AMPLIFICATION AND SEQUENCING PRIMER PAIRS AND USE THEREOF | Oasis Biosciences, Inc. (US) | 2002-01-16 | — | — | EP | disclosed |
| WO-2000061807-A1 | AMPLIFICATION AND SEQUENCING PRIMER PAIRS AND USE THEREOF | OASIS BIOSCIENCES, INC. (US) | 2000-10-19 | — | — | WO | disclosed |
| EP-1019539-A1 | COMBINATORIAL ANTISENSE LIBRARY | Oasis Biosciences, Inc. (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1999018238-A1 | COMBINATORIAL ANTISENSE LIBRARY | OASIS BIOSCIENCES, INC. (US) | 1999-04-15 | — | — | WO | disclosed |