Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28997652 | 0.92 | HRH3 (0.42) | HRH3HSD11B1 | |
| SCHEMBL28805725 | 0.90 | L3MBTL3 (0.46) | HRH3 | |
| SCHEMBL467634 | 0.90 | ACVR1 (0.41) | HRH3 | |
| SCHEMBL30090827 | 0.90 | ACVR1 (0.41) | HRH3 | |
| SCHEMBL27919685 | 0.89 | L3MBTL3 (0.44) | HRH3 | |
| SCHEMBL27901888 | 0.89 | L3MBTL3 (0.44) | HRH3 | |
| SCHEMBL467882 | 0.83 | HRH4 (0.48) | HRH3 | |
| SCHEMBL27767974 | 0.83 | ADORA2A (0.39) | — | |
| SCHEMBL27789437 | 0.82 | CXCR3 (0.36) | — | |
| SCHEMBL28802365 | 0.79 | CASP1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101622248-B | N3-heteroaryl substituted triazoles and n5-heteroaryl substituted triazoles useful as AXL inhibitors | RIGEL PHARMACEUTICALS INC | 2013-04-17 | — | — | CN | claimed |
| CN-101622248-A | N3-heteroaryl substituted triazoles and N5-heteroaryl substituted triazoles useful as AXL inhibitors | RIGEL PHARMACEUTICALS INC | 2010-01-06 | — | — | CN | claimed |
| CN-101622248-B | N3-heteroaryl substituted triazoles and n5-heteroaryl substituted triazoles useful as AXL inhibitors | RIGEL PHARMACEUTICALS INC | 2013-04-17 | — | — | CN | disclosed |
| CN-101622248-A | N3-heteroaryl substituted triazoles and N5-heteroaryl substituted triazoles useful as AXL inhibitors | RIGEL PHARMACEUTICALS INC | 2010-01-06 | — | — | CN | disclosed |