Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | F12 | P00748 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27767958 | 0.92 | HRH3 (0.42) | HRH3HSD11B1 | |
| SCHEMBL28805725 | 0.90 | L3MBTL3 (0.46) | HRH3L3MBTL3L3MBTL1 | |
| SCHEMBL27901888 | 0.89 | L3MBTL3 (0.44) | HRH3L3MBTL3L3MBTL1 | |
| SCHEMBL27919685 | 0.89 | L3MBTL3 (0.44) | HRH3L3MBTL3L3MBTL1 | |
| SCHEMBL30090827 | 0.84 | ACVR1 (0.41) | HRH3 | |
| SCHEMBL467634 | 0.84 | ACVR1 (0.41) | HRH3 | |
| SCHEMBL467882 | 0.78 | HRH4 (0.48) | HRH3MAP4K4 | |
| SCHEMBL27767974 | 0.78 | ADORA2A (0.39) | — | |
| SCHEMBL28802365 | 0.76 | CASP1 (0.39) | — | |
| SCHEMBL27789437 | 0.75 | CXCR3 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116075303-A | Method of selecting patients treated with a combination of an AXL inhibitor and an immune checkpoint modulator | 卑尔根生物股份公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-115916344-A | AXL inhibitors for antiviral therapy | 卑尔根生物股份公司 | 2023-04-04 | — | — | CN | disclosed |