SCHEMBL2776799

SCHEMBL2776799

CCc1c[c]c(C)cc1O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.36
ALOX12 P18054 1/20 0.36
MCL1 Q07820 2/20 0.36
ALDH1A1 P00352 3/20 0.34
MAPK1 P28482 3/20 0.34
HTT P42858 3/20 0.34
KDM4E B2RXH2 3/20 0.34
MAPT P10636 3/20 0.34
MEN1 O00255 2/20 0.34
POLB P06746 2/20 0.34
THRB P10828 2/20 0.34
KMT2A Q03164 2/20 0.34
HKDC1 Q2TB90 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
APEX1 P27695 1/20 0.34
RECQL P46063 1/20 0.34
CACNA1B Q00975 1/20 0.34
APBA1 Q02410 1/20 0.34
ESR1 P03372 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5565377 0.83 HMGCR (0.44) ALOX15ALOX12MCL1ALDH1A1MAPK1
SCHEMBL28045776 0.80 TYR (0.50) ALOX15ALDH1A1MAPK1HTTKDM4E
SCHEMBL28093181 0.80 ALOX15 (0.38) ALOX15ALOX12MCL1ALDH1A1MAPK1
SCHEMBL15063717 0.79 GRIN2D (0.34) ALOX15ALOX12
SCHEMBL1819061 0.77 NOS3 (0.38)
SCHEMBL929797 0.74
SCHEMBL11778281 0.73 NOS3 (0.33)
SCHEMBL930869 0.72
SCHEMBL1760478 0.70 ALOX15 (0.54) ALOX15ALOX12MCL1ALDH1A1MAPK1
SCHEMBL27530957 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10428216-B2 Golf ball incorporating a mixture of a thermoset and/or thermoplastic composition and a plurality of conductive nanoshelled structures ACUSHNET COMPANY (US) 2019-10-01 US disclosed
US-20190192922-A1 GOLF BALL COMPRISING MEDIUM HARDNESS GRADIENT CORE ACUSHNET COMPANY (US) 2019-06-27 US disclosed
US-10252115-B2 Golf ball incorporating positive hardness gradient thermoset polyurethane outer cover layer ACUSHNET COMPANY (US) 2019-04-09 US disclosed
US-10220263-B2 Golf balls comprising medium hardness gradient core ACUSHNET COMPANY (US) 2019-03-05 US disclosed
US-10130848-B2 Golf ball multilayer core having a gradient quotient ACUSHNET COMPANY (US) 2018-11-20 US disclosed
US-20180318654-A1 GOLF BALL INCORPORATING POSITIVE HARDNESS GRADIENT THERMOSET POLYURETHANE OUTER COVER LAYER ACUSHNET COMPANY (US) 2018-11-08 US disclosed
US-10112081-B2 Golf ball incorporating positive hardness gradient thermoset polyurethane outer cover layer ACUSHNET COMPANY (US) 2018-10-30 US disclosed
US-10035046-B2 Multilayer core golf ball having hardness gradient within and between each core layer ACUSHNET COMPANY (US) 2018-07-31 US disclosed
US-10029151-B2 Multi-layer cover golf ball having a high acid casing layer ACUSHNET COMPANY (US) 2018-07-24 US disclosed
US-10029150-B2 Golf ball having medium positive gradient quotient and low trans content ACUSHNET COMPANY (US) 2018-07-24 US disclosed
US-20090023865-A1 Method of Treating Rubber Composition with Cure Inhibitor to Create Soft Skin in Golf Ball Core JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2009-01-22 US disclosed
US-20090011863-A1 Negative Hardness Gradient Inner Core for Dual Core Golf Ball JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2009-01-08 US disclosed
US-20090008832-A1 Negative Hardness Gradient Core Produced from a Low, Temperature-Based Cure Cycle Index ACUSHNET COMPANY 2009-01-08 US disclosed
US-20090011866-A1 Multi-Layer Core Golf Ball Having Opposing Hardness Gradient with Steep Gradient Inner Core Layer JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2009-01-08 US disclosed
US-20090011859-A1 Negative Hardness Gradient Inner Core for Dual Core Golf Ball JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2009-01-08 US disclosed
US-7429221-B1 Negative hardness gradient outer core layer for dual core golf ball ACUSHNET COMPANY (US) 2008-09-30 US disclosed
US-20080153629-A1 Thick Outer Cover Layer Golf Ball ACUSHNET COMPANY 2008-06-26 US disclosed
US-20080146380-A1 Thick Outer Cover Layer Golf Ball ACUSHNET COMPANY 2008-06-19 US disclosed
US-20080146378-A1 Thick Inner Cover Multi-layer Golf Ball JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2008-06-19 US disclosed
US-3984940-A Degradable plastic REICH MURRAY 1976-10-12 US disclosed