SCHEMBL5565377

SCHEMBL5565377

CCCc1c[c]c(C)cc1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 2/20 0.44
PTPN1 P18031 1/20 0.37
PTPN11 Q06124 1/20 0.37
TYR P14679 3/20 0.36
HTT P42858 4/20 0.35
ALDH1A1 P00352 4/20 0.35
MAPK1 P28482 2/20 0.34
HPGD P15428 2/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
CNR1 P21554 1/20 0.34
CNR2 P34972 1/20 0.34
MAPT P10636 5/20 0.34
MEN1 O00255 4/20 0.34
KMT2A Q03164 4/20 0.34
TDP1 Q9NUW8 3/20 0.34
ALOX5 P09917 2/20 0.34
TP53 P04637 2/20 0.34
ALOX15 P16050 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28045776 0.89 TYR (0.50) HMGCRTYRHTTALDH1A1MAPK1
SCHEMBL2776799 0.83 ALOX15 (0.36) HTTALDH1A1MAPK1HPGDMAPT
SCHEMBL28932575 0.82 HMGCR (0.46) HMGCRPTPN1PTPN11TYRHTT
SCHEMBL1760537 0.73 HMGCR (0.64) HMGCRPTPN1PTPN11TYRHTT
SCHEMBL11024762 0.71 HMGCR (0.61) HMGCRPTPN1PTPN11TYRHTT
SCHEMBL929797 0.71
SCHEMBL4656377 0.71 TYR (0.52) HMGCRTYRHTTALDH1A1MAPK1
SCHEMBL9056784 0.69 TYR (0.50) HMGCRTYRHTTALDH1A1MAPK1
SCHEMBL930869 0.69
SCHEMBL11840310 0.69 HMGCR (0.59) HMGCRPTPN1PTPN11TYRHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7198884-B2 Heat stable photocurable resin composition for dry film resist CIBA SPECIALTY CHEMICALS CORP. (US) 2007-04-03 US disclosed
US-20050260520-A1 Heat stable photocurable resin composition for dry film resist CIBA SPECIALTY CHEMICALS CORP. 2005-11-24 US disclosed
US-20040157947-A1 Polymeric material, containing a latent acid CIBA SPECIALTY CHEMICALS CORP. 2004-08-12 US disclosed