Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1793285 | 0.82 | ACHE (0.52) | ACHEKMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL1789986 | 0.81 | ACHE (0.51) | ACHEKMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL3936937 | 0.78 | NAAA (0.41) | ACHEALDH1A1F2POLB | |
| SCHEMBL13271217 | 0.71 | CYP2C9 (0.45) | ACHEKMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL3406197 | 0.69 | ACHE (0.52) | ACHEKMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL27768004 | 0.69 | ACHE (0.47) | ACHEKMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL10782553 | 0.68 | ACHE (0.71) | ACHEKMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL11444965 | 0.67 | ACHE (0.69) | ACHEKMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL1787633 | 0.67 | CYP3A4 (0.53) | ACHEKMT2AMEN1ALDH1A1HTR2C | |
| SCHEMBL1792243 | 0.66 | KMO (0.54) | ACHEKMT2AMEN1HTR2CPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101490001-A | Substituted phenylacetic acids as DP-2 antagonists | ICOS CORP (US) | 2009-07-22 | — | — | CN | disclosed |