Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 6/20 | 0.38 |
| ▸ | DRD2 | P14416 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | BCL9 | O00512 | 5/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 3/20 | 0.37 |
| ▸ | DRD4 | P21917 | 3/20 | 0.37 |
| ▸ | DRD5 | P21918 | 3/20 | 0.37 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | USP5 | P45974 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27768051 | 0.91 | BCL9 (0.39) | DRD3DRD2NPC1MAPTHPGD | |
| SCHEMBL27746990 | 0.84 | ALDH1A1 (0.39) | DRD3DRD2BCL9CTNNB1ALDH1A1 | |
| SCHEMBL3933452 | 0.83 | FKBP1A (0.46) | DRD3DRD2NPC1MAPTHPGD | |
| SCHEMBL27768152 | 0.80 | DRD3 (0.42) | DRD3DRD2BCL9CTNNB1DRD1 | |
| SCHEMBL3941700 | 0.78 | BCL9 (0.54) | HPGDSMN1; SMN2BCL9CTNNB1ALDH1A1 | |
| SCHEMBL3933032 | 0.78 | ALDH1A1 (0.54) | MAPTHPGDSMN1; SMN2ALDH1A1POLB | |
| SCHEMBL27747181 | 0.78 | ALDH1A1 (0.38) | DRD3DRD2SMN1; SMN2BCL9CTNNB1 | |
| SCHEMBL3939587 | 0.77 | DRD3 (0.47) | DRD3DRD2BCL9CTNNB1ALDH1A1 | |
| 1,2-Dichlorobenzene SCHEMBL27768082 | 0.76 | ALDH1A1 (0.40) | DRD3DRD2MAPTSMN1; SMN2BCL9 | |
| Fluorobenzene SCHEMBL27747102 | 0.76 | TSHR (0.41) | DRD3DRD2NPC1RAB9ABCL9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101490001-A | Substituted phenylacetic acids as DP-2 antagonists | ICOS CORP (US) | 2009-07-22 | — | — | CN | claimed |
| CN-101490001-A | Substituted phenylacetic acids as DP-2 antagonists | ICOS CORP (US) | 2009-07-22 | — | — | CN | disclosed |