Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 5/20 | 0.47 |
| ▸ | DRD2 | P14416 | 4/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD5 | P21918 | 1/20 | 0.46 |
| ▸ | BCL9 | O00512 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | FABP6 | P51161 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3943769 | 0.88 | DRD2 (0.45) | DRD3DRD2DRD1DRD4DRD5 | |
| SCHEMBL3930676 | 0.87 | BCL9 (0.49) | DRD3DRD2BCL9CTNNB1 | |
| SCHEMBL3941700 | 0.86 | BCL9 (0.54) | BCL9CTNNB1ALDH1A1 | |
| SCHEMBL3933032 | 0.86 | ALDH1A1 (0.54) | ALDH1A1POLB | |
| SCHEMBL3933831 | 0.85 | DRD3 (0.47) | DRD3DRD2DRD1DRD4DRD5 | |
| SCHEMBL3932070 | 0.85 | ALDH1A1 (0.50) | DRD3DRD2DRD1DRD4DRD5 | |
| SCHEMBL3930804 | 0.84 | DRD2 (0.46) | DRD3DRD2DRD1DRD4DRD5 | |
| SCHEMBL3937652 | 0.84 | MEN1 (0.50) | DRD3DRD2BCL9CTNNB1ALDH1A1 | |
| SCHEMBL3939581 | 0.84 | BCL9 (0.52) | DRD3DRD2DRD1DRD4DRD5 | |
| SCHEMBL3936225 | 0.84 | BCL9 (0.48) | DRD3DRD2DRD1DRD4DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101490001-A | Substituted phenylacetic acids as DP-2 antagonists | ICOS CORP (US) | 2009-07-22 | — | — | CN | claimed |
| CN-101490001-A | Substituted phenylacetic acids as DP-2 antagonists | ICOS CORP (US) | 2009-07-22 | — | — | CN | disclosed |
| EP-2044017-A2 | SUBSTITUTED PHENYL ACETIC ACIDS AS DP-2 ANTAGONISTS | ICOS CORPORATION (US) | 2009-04-08 | — | — | EP | disclosed |
| WO-2007146838-A2 | SUBSTITUTED PHENYL ACETIC ACIDS AS DP-2 ANTAGONISTS | ICOS CORPORATION (US) | 2007-12-21 | — | — | WO | disclosed |
| WO-2007146838-A2 | SUBSTITUTED PHENYL ACETIC ACIDS AS DP-2 ANTAGONISTS | ICOS CORPORATION (US) | 2007-12-21 | — | — | WO | disclosed |