Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.49 |
| ▸ | GRM6 | O15303 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | ILK | Q13418 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9586899 | 0.86 | ILK (0.43) | ALDH1A1KDM4EHPGDILKPOLB | |
| SCHEMBL9586392 | 0.84 | JAK2 (0.46) | ALDH1A1HSD17B10KDM4EHPGDILK | |
| SCHEMBL9586819 | 0.84 | GRM6 (0.54) | ALDH1A1GRM6KDM4EHPGDILK | |
| SCHEMBL9587231 | 0.83 | KDM4E (0.49) | ALDH1A1HSD17B10KDM4EHPGDTSHR | |
| SCHEMBL2301473 | 0.81 | KDM4E (0.62) | ALDH1A1HSD17B10GRM6KDM4EHPGD | |
| SCHEMBL9586307 | 0.80 | CDC7 (0.47) | ALDH1A1HSD17B10GRM6KDM4EHPGD | |
| SCHEMBL5731992 | 0.76 | ALDH1A1 (0.55) | ALDH1A1HSD17B10KDM4EHPGDILK | |
| SCHEMBL9586920 | 0.76 | ALDH1A1 (0.52) | ALDH1A1KDM4EHPGDPOLBTSHR | |
| SCHEMBL1179173 | 0.75 | ALDH1A1 (0.49) | ALDH1A1HSD17B10KDM4EHPGDPOLB | |
| SCHEMBL9585434 | 0.75 | TARBP2 (0.51) | ALDH1A1KDM4EHPGDMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101605784-B | Aza-bridged-ring compound | ASTELLAS PHARMA INC JP | 2013-04-10 | — | — | CN | disclosed |
| CN-101605784-A | Aza-bridged-ring compound | ASTELLAS PHARMA INC (JP) | 2009-12-16 | — | — | CN | disclosed |