Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9586899 | 0.85 | ILK (0.43) | KDM4EHPGDMAPTALDH1A1TSHR | |
| SCHEMBL27584218 | 0.84 | GAA (0.43) | KDM4EHPGDHSD17B10MAPTALDH1A1 | |
| SCHEMBL27768167 | 0.83 | ALDH1A1 (0.49) | KDM4EHPGDRAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL9586819 | 0.83 | GRM6 (0.54) | KDM4EHPGDRAB9AMAPTALDH1A1 | |
| SCHEMBL9586392 | 0.83 | JAK2 (0.46) | KDM4EHPGDRAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL2301473 | 0.80 | KDM4E (0.62) | KDM4EHPGDRAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL1560797 | 0.80 | PTPN1 (0.47) | KDM4EHPGDRAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL9586307 | 0.79 | CDC7 (0.47) | KDM4EHPGDRAB9AHSD17B10MAPT | |
| SCHEMBL9585425 | 0.78 | HPGD (0.45) | KDM4EHPGDRAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL31325698 | 0.78 | HTT (0.46) | KDM4EHPGDSMN1; SMN2HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5204482-A | Ethylenediamine monoamide heteroaryl derivatives | HOFFMAN-LAROCHE INC. (US) | 1993-04-20 | — | — | US | disclosed |
| US-5011849-A | Monoamine oxidase inhibitors | HOFFMANN-LA ROCHE INC. (US) | 1991-04-30 | — | — | US | disclosed |