Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28784637 | 0.77 | LTA4H (0.51) | MEN1KMT2AMAPK1POLBRAB9A | |
| SCHEMBL16861315 | 0.77 | AR (0.46) | ARHTR2CKMT2AMAPK1HSD17B10 | |
| SCHEMBL16861292 | 0.76 | AR (0.45) | ARHTR2CHSD17B10IDO1ALDH1A1 | |
| SCHEMBL27789658 | 0.75 | ROCK2 (0.48) | MEN1KMT2ARAB9AMAPTGAA | |
| SCHEMBL28114539 | 0.75 | RAB9A (0.53) | LMNAPOLBRAB9AHSD17B10ALDH1A1 | |
| SCHEMBL7276901 | 0.74 | AR (0.55) | ARHTR2CHSD17B10IDO1GAA | |
| SCHEMBL5113969 | 0.73 | RAB9A (0.52) | LMNAMEN1KMT2APOLBRAB9A | |
| SCHEMBL12298063 | 0.73 | RAB9A (0.55) | LMNAMEN1KMT2APKMPOLB | |
| SCHEMBL28944524 | 0.72 | AR (0.49) | ARLMNAMEN1KMT2AMAPK1 | |
| SCHEMBL20239625 | 0.72 | NR1H2 (0.49) | LMNAMEN1KMT2AMAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100572381-C | Pyrazolonaphthyridine derivative | ASKA PHARM CO LTD (JP) | 2009-12-23 | — | — | CN | disclosed |