Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.62 |
| ▸ | NPC1 | O15118 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10977960 | 0.87 | RAB9A (0.63) | RAB9ANPC1ALDH1A1MAPTLMNA | |
| SCHEMBL31159595 | 0.85 | ALDH1A1 (0.63) | RAB9ANPC1ALDH1A1MAPTLMNA | |
| SCHEMBL1704376 | 0.83 | ALDH1A1 (0.71) | RAB9ANPC1ALDH1A1MAPTLMNA | |
| SCHEMBL11591034 | 0.83 | ALDH1A1 (0.67) | RAB9ANPC1ALDH1A1MAPTLMNA | |
| SCHEMBL8396995 | 0.82 | NPC1 (0.72) | RAB9ANPC1ALDH1A1MAPTLMNA | |
| SCHEMBL1532370 | 0.81 | MAPT (0.66) | RAB9ANPC1ALDH1A1MAPTLMNA | |
| SCHEMBL10889343 | 0.80 | ALDH1A1 (0.63) | RAB9ANPC1ALDH1A1MAPTLMNA | |
| SCHEMBL5523947 | 0.80 | KCNMA1 (0.64) | RAB9ANPC1ALDH1A1MAPTLMNA | |
| SCHEMBL6004947 | 0.79 | CYP1A2 (0.65) | RAB9ANPC1ALDH1A1MAPTLMNA | |
| SCHEMBL2884065 | 0.79 | ALDH1A1 (0.59) | RAB9ANPC1ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101426778-A | N-substituted-azacyclylamines as histamine-3 antagonists | WYETH CORP (US) | 2009-05-06 | — | — | CN | disclosed |