Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 3/20 | 0.39 |
| ▸ | CFB | P00751 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ACLY | P53396 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3928274 | 0.81 | TRPA1 (0.57) | FKBP1ATSHRPSEN1PSEN2APH1B | |
| Fluorobenzene SCHEMBL27747055 | 0.80 | PSEN1 (0.36) | FKBP1AACLYPSEN1PSEN2APH1B | |
| Fluorobenzene SCHEMBL27747102 | 0.80 | TSHR (0.41) | PKMTSHRLMNA | |
| Fluorobenzene SCHEMBL28776689 | 0.79 | PKM (0.39) | PKMTSHRSIGMAR1MAPK1 | |
| SCHEMBL27746991 | 0.73 | PTGDR2 (0.42) | PKMTSHRSIGMAR1LMNAMAPT | |
| Fluorobenzene SCHEMBL28781330 | 0.72 | TSHR (0.39) | PKMTSHRLMNAMAPT | |
| SCHEMBL3942322 | 0.71 | TRPA1 (0.47) | FKBP1ATSHRPSEN1PSEN2APH1B | |
| Fluorobenzene SCHEMBL27746993 | 0.71 | LMNA (0.41) | PKMTSHRLMNAMAPT | |
| 1,2-Dichlorobenzene SCHEMBL27768082 | 0.71 | ALDH1A1 (0.40) | LMNAMAPT | |
| Chlorobenzene SCHEMBL27747084 | 0.71 | DRD3 (0.39) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101490001-A | Substituted phenylacetic acids as DP-2 antagonists | ICOS CORP (US) | 2009-07-22 | — | — | CN | disclosed |