Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MELK | Q14680 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MTOR | P42345 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.37 |
| ▸ | RPTOR | Q8N122 | 3/20 | 0.37 |
| ▸ | MLST8 | Q9BVC4 | 3/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL70114 | 0.83 | NPC1 (0.63) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E | |
| Water SCHEMBL17731583 | 0.81 | NPC1 (0.61) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL27793417 | 0.81 | HPGDS (0.43) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL18586422 | 0.81 | MTOR (0.56) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL1002407 | 0.80 | SMN1; SMN2 (0.44) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL18586388 | 0.80 | ALDH1A1 (0.53) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL8415523 | 0.80 | MTOR (0.52) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL21281739 | 0.80 | SMN1; SMN2 (0.47) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL1990298 | 0.80 | MTOR (0.52) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL18586366 | 0.80 | PTGS2 (0.47) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111686110-B | Compounds and compositions for modulating EGFR mutant kinase activity | 株式会社柳韩洋行 | 2023-06-16 | — | — | CN | disclosed |
| CN-102850324-A | Indole compounds | MICROBIA INC | 2013-01-02 | — | — | CN | disclosed |
| CN-101563337-A | Indole compounds | MICROBIA INC (US) | 2009-10-21 | — | — | CN | disclosed |