SCHEMBL538188

SCHEMBL538188

CSCC[C@H](C(=O)O)N(OCc1ccccc1)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 2/20 0.38
LTA4H P09960 1/20 0.38
MME P08473 1/20 0.38
ALDH1A1 P00352 1/20 0.37
FNTA P49354 1/20 0.37
FNTB P49356 1/20 0.37
GAA P10253 1/20 0.36
POLB P06746 1/20 0.36
CHRNB2 P17787 1/20 0.36
CHRNB4 P30926 1/20 0.36
CHRNA3 P32297 1/20 0.36
CHRNA4 P43681 1/20 0.36
CA1 P00915 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1086440 0.80 SLC1A1 (0.39) LTA4HMME
SCHEMBL1087097 0.80 SLC1A1 (0.39) LTA4HMME
SCHEMBL27768608 0.79 ANPEP (0.42) ANPEPLTA4HFNTAFNTBGAA
SCHEMBL6681598 0.79 ANPEP (0.42) ANPEPLTA4HFNTAFNTBGAA
SCHEMBL11129467 0.79 CPA1 (0.44) LTA4HALDH1A1
SCHEMBL8664225 0.78 EPOR (0.51) LTA4H
SCHEMBL6372184 0.77 FOLH1 (0.47) ANPEPMMEALDH1A1FNTAFNTB
SCHEMBL9081277 0.77 NPC1 (0.42) ANPEPLTA4HALDH1A1CHRNB2CHRNB4
SCHEMBL3644349 0.75 ALDH1A1 (0.44) ANPEPLTA4HMMEALDH1A1FNTA
Glycine SCHEMBL28734973 0.75 FOLH1 (0.38) MME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2413711-B1 DIPEPTIDE AS FEEDSTUFF ADDITIVE EVONIK DEGUSSA GMBH (DE) 2014-08-06 EP disclosed
US-20140205711-A1 DIPEPTIDES AS FEED ADDITIVES EVONIK DEGUSSA GMBH (DE) 2014-07-24 US disclosed
EP-2413711-A1 DIPEPTIDE AS FEEDSTUFF ADDITIVE Evonik Degussa GmbH (DE) 2012-02-08 EP disclosed
WO-2010112365-A1 DIPEPTIDE AS FEEDSTUFF ADDITIVE EVONIK DEGUSSA GMBH (DE) 2010-10-07 WO disclosed
US-20100247707-A1 DIPEPTIDES AS FEED ADDITIVES EVONIK DEGUSSA GMBH (DE) 2010-09-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100247707-A1 DIPEPTIDES AS FEED ADDITIVES AADAT, BCAT2, SLC7A11 ANPEP 52/4885LTA4H 1775/4885MME 429/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.