Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.47 |
| ▸ | TKT | P29401 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26627835 | 0.98 | LMNA (0.53) | LMNATLR8TKTKDM4E | |
| SCHEMBL1554275 | 0.84 | PKM (0.55) | — | |
| SCHEMBL29352921 | 0.84 | PKM (0.55) | — | |
| SCHEMBL30872658 | 0.82 | PKM (0.54) | — | |
| SCHEMBL9499492 | 0.82 | PKM (0.54) | — | |
| SCHEMBL16701417 | 0.82 | PKM (0.54) | — | |
| SCHEMBL16701413 | 0.82 | PKM (0.54) | — | |
| SCHEMBL30042167 | 0.81 | TLR8 (0.46) | TLR8 | |
| Benzene SCHEMBL27894272 | 0.81 | PKM (0.52) | TLR8 | |
| SCHEMBL28095152 | 0.81 | TLR8 (0.46) | TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101627017-B | Process for the manufacture of vitamin B1 precursor | DSM IP ASSETS BV | 2013-02-27 | — | — | CN | disclosed |
| CN-101627017-A | Process for the manufacture of vitamin B1 precursor | DSM IP ASSETS BV | 2010-01-13 | — | — | CN | disclosed |