SCHEMBL28095152

SCHEMBL28095152

CCCCCc1cnc(O)nc1N

nearest known ligand 0.46

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 14/20 0.46
DHFR P00374 1/20 0.40
PKM P14618 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29352921 0.82 PKM (0.55) DHFRPKM
SCHEMBL1554275 0.82 PKM (0.55) DHFRPKM
SCHEMBL16701413 0.81 PKM (0.54) DHFRPKM
SCHEMBL27768609 0.81 LMNA (0.54) TLR8
SCHEMBL16701417 0.81 PKM (0.54) DHFRPKM
SCHEMBL9499492 0.81 PKM (0.54) DHFRPKM
SCHEMBL30872658 0.81 PKM (0.54) DHFRPKM
SCHEMBL30042167 0.79 TLR8 (0.46) TLR8PKM
Benzene SCHEMBL27894272 0.79 PKM (0.52) TLR8DHFRPKM
SCHEMBL26627835 0.79 LMNA (0.53) TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106029644-A Thiopyranose compound and method for producing same 富士胶片株式会社 2016-10-12 CN disclosed