SCHEMBL27768674

SCHEMBL27768674

O=C(c1ncc(-c2cccnc2)o1)c1ncc(-c2cccnc2)o1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 0.55
ALDH1A1 P00352 3/20 0.53
KDM4E B2RXH2 2/20 0.53
HPGD P15428 2/20 0.53
NPC1 O15118 1/20 0.53
RAB9A P51151 1/20 0.53
HSD17B10 Q99714 1/20 0.53
CYP2A6 P11509 8/20 0.47
CYP3A4 P08684 7/20 0.47
CYP2E1 P05181 4/20 0.47
CYP2D6 P10635 4/20 0.47
CYP2C9 P11712 4/20 0.47
CYP2B6 P20813 4/20 0.47
CYP2C19 P33261 4/20 0.47
CYP1A2 P05177 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.44
MKNK1 Q9BUB5 1/20 0.44
MKNK2 Q9HBH9 1/20 0.44
TUBB4A P04350 1/20 0.43
TUBB P07437 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2724813 0.89 ALDH1A1 (0.55) FAAHALDH1A1KDM4EHPGDNPC1
SCHEMBL5105714 0.87 ALDH1A1 (0.54) FAAHALDH1A1KDM4EHPGDNPC1
Lithium Ion SCHEMBL5105709 0.86 FAAH (0.52) FAAHALDH1A1KDM4EHPGDNPC1
SCHEMBL27768454 0.82 TUBB4A (0.59) FAAHALDH1A1KDM4EHPGDNPC1
SCHEMBL27789997 0.81 FAAH (0.51) FAAHALDH1A1KDM4EHPGDNPC1
SCHEMBL5111369 0.80 FAAH (0.56) FAAHALDH1A1KDM4EHPGDNPC1
SCHEMBL2779211 0.77 FAAH (0.71) FAAH
SCHEMBL2724814 0.75 ALDH1A1 (0.51) FAAHALDH1A1KDM4EHPGDNPC1
SCHEMBL30301340 0.75 TUBB4A (0.55) FAAHALDH1A1KDM4EHPGDNPC1
SCHEMBL27605095 0.75 CYP2A6 (0.57) ALDH1A1KDM4ENPC1RAB9ACYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102850324-A Indole compounds MICROBIA INC 2013-01-02 CN disclosed
CN-101563337-A Indole compounds MICROBIA INC (US) 2009-10-21 CN disclosed