Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.70 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.70 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | HPGDS | O60760 | 2/20 | 0.60 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | ATM | Q13315 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | NPY1R | P25929 | 1/20 | 0.59 |
| ▸ | NPY2R | P49146 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1683594 | 0.91 | HDAC1 (0.64) | HDAC1HDAC8HDAC6TDP1HPGDS | |
| SCHEMBL1683722 | 0.90 | TLR7 (0.72) | HDAC1HDAC8HDAC6TDP1HPGDS | |
| SCHEMBL352152 | 0.89 | HPGDS (0.73) | HDAC1HDAC8HDAC6TDP1HPGDS | |
| Hydrochloric Acid SCHEMBL6821751 | 0.87 | HPGDS (0.71) | HDAC1HDAC8HDAC6TDP1HPGDS | |
| SCHEMBL786691 | 0.85 | HDAC1 (0.57) | HDAC1HDAC8HDAC6TDP1HPGDS | |
| SCHEMBL1574742 | 0.85 | HDAC1 (0.66) | HDAC1HDAC8HDAC6TDP1HPGDS | |
| SCHEMBL168519 | 0.85 | HTR2B (0.66) | HDAC1HDAC8HDAC6TDP1HPGDS | |
| SCHEMBL26319518 | 0.85 | ALDH1A1 (0.73) | HDAC1HDAC8HDAC6TDP1HPGDS | |
| SCHEMBL168291 | 0.85 | TDP1 (0.67) | HDAC1HDAC8HDAC6TDP1HPGDS | |
| SCHEMBL27768683 | 0.85 | HPGD (0.68) | HDAC1HDAC8HDAC6TDP1TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102137592-A | Compounds for the treatment of cancer | UNIV TENNESSEE RES FOUNDATION (US) | 2011-07-27 | — | — | CN | claimed |
| CN-102850324-A | Indole compounds | MICROBIA INC | 2013-01-02 | — | — | CN | disclosed |
| CN-102137592-A | Compounds for the treatment of cancer | UNIV TENNESSEE RES FOUNDATION (US) | 2011-07-27 | — | — | CN | disclosed |
| CN-102083839-A | Compound (I) | ASTRAZENECA AB | 2011-06-01 | — | — | CN | disclosed |
| CN-101563337-A | Indole compounds | MICROBIA INC (US) | 2009-10-21 | — | — | CN | disclosed |