Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.51 |
| ▸ | IDE | P14735 | 1/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL657641 | 0.87 | ALDH1A1 (0.70) | HPGDLMNAMAPTKMT2AMEN1 | |
| SCHEMBL4735788 | 0.85 | HPGD (0.64) | HPGDLMNAMAPTKMT2AMEN1 | |
| SCHEMBL6202834 | 0.85 | HPGD (0.64) | HPGDLMNAMAPTKMT2AMEN1 | |
| SCHEMBL8278408 | 0.85 | HPGD (0.69) | HPGDLMNAMAPTKMT2AMEN1 | |
| SCHEMBL27768678 | 0.85 | HDAC1 (0.70) | HPGDLMNAMAPTKMT2AMEN1 | |
| SCHEMBL11118469 | 0.82 | HPGD (0.60) | HPGDLMNAMAPTKMT2AMEN1 | |
| SCHEMBL28784680 | 0.81 | HDAC6 (0.74) | MAPTMAPK1ALDH1A1HDAC6TLR7 | |
| SCHEMBL2555278 | 0.81 | HPGD (0.72) | HPGDLMNAMAPTKMT2AMEN1 | |
| SCHEMBL2551476 | 0.81 | HPGD (0.68) | HPGDLMNAMAPTKMT2AMEN1 | |
| SCHEMBL11118491 | 0.81 | HPGD (0.59) | HPGDLMNAMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102850324-A | Indole compounds | MICROBIA INC | 2013-01-02 | — | — | CN | disclosed |
| CN-101563337-A | Indole compounds | MICROBIA INC (US) | 2009-10-21 | — | — | CN | disclosed |