Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GLS | O94925 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31735617 | 0.77 | KMT2A (0.49) | KMT2AMEN1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL2264810 | 0.77 | MAPT (0.54) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL1252366 | 0.76 | CCR2 (0.51) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL27361127 | 0.75 | PKM (0.53) | KMT2AMEN1MAPTLMNACYP19A1 | |
| SCHEMBL2073705 | 0.75 | MEN1 (0.53) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL3571117 | 0.74 | IRAK4 (0.49) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL3481105 | 0.72 | CYP19A1 (0.61) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL31036289 | 0.72 | CYP19A1 (0.61) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL7962237 | 0.72 | AR (0.60) | KMT2AMEN1GAASMN1; SMN2MAPT | |
| SCHEMBL4553137 | 0.72 | CYP1A2 (0.43) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101466709-A | 1, 5 and 3, 6-substituted indole compounds having NOS inhibitory activity | NEURAXON INC (CA) | 2009-06-24 | — | — | CN | disclosed |