Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27532542 | 0.91 | PLA2G2A (0.50) | PKMCYP19A1CNR2ARHPGD | |
| SCHEMBL7962237 | 0.87 | AR (0.60) | CYP19A1ARL3MBTL1MAPTMEN1 | |
| SCHEMBL31735617 | 0.79 | KMT2A (0.49) | PKMCYP19A1HPGDMAPTMEN1 | |
| SCHEMBL2846720 | 0.79 | PKM (0.62) | PKMCYP19A1CNR2SIGMAR1 | |
| SCHEMBL2264810 | 0.79 | MAPT (0.54) | CYP19A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL19538865 | 0.79 | KMT2A (0.59) | PKMMAPTMEN1KMT2ABRD4 | |
| SCHEMBL2125241 | 0.79 | KMT2A (0.52) | PKMCYP19A1CNR2HPGDMAPT | |
| SCHEMBL6018659 | 0.78 | ECE1 (0.63) | PKMCNR2MAPTMEN1KMT2A | |
| SCHEMBL1252366 | 0.77 | CCR2 (0.51) | CYP19A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL27730441 | 0.77 | MAPT (0.73) | PKMCNR2L3MBTL1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1068588-C | 1H-indole-3-acetamide splA2 inhibitors | LILLY CO ELI (US) | 2001-07-18 | — | — | CN | disclosed |