SCHEMBL27768998

SCHEMBL27768998

Cn1ccc2cc(-c3ccc(C(=O)O)c(N)c3)ccc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPM1B O75688 1/20 0.50
PRKCI P41743 1/20 0.49
AR P10275 1/20 0.46
HSD11B1 P28845 1/20 0.45
FASN P49327 1/20 0.44
CCNC P24863 2/20 0.44
CDK8 P49336 2/20 0.44
KDM4E B2RXH2 1/20 0.44
GFER P55789 1/20 0.44
KMT2A Q03164 1/20 0.44
RXFP1 Q9HBX9 1/20 0.44
LRRK2 Q5S007 1/20 0.43
CYP2A6 P11509 1/20 0.42
CD274 Q9NZQ7 1/20 0.41
PRKAG1 P54619 1/20 0.41
PRKAA2 P54646 1/20 0.41
PRKAA1 Q13131 1/20 0.41
PRKAB1 Q9Y478 1/20 0.41
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3477996 0.79 PRKCI (0.54) PRKCIARHSD11B1FASNKDM4E
SCHEMBL4896703 0.78 HSD11B1 (0.46) PRKCIARHSD11B1FASNCCNC
SCHEMBL29436316 0.78 PPM1B (0.75) PPM1BKDM4EGFERKMT2ARXFP1
SCHEMBL710309 0.78 PPM1B (0.75) PPM1BKDM4EGFERKMT2ARXFP1
SCHEMBL23499274 0.76 PPM1B (0.79) PPM1BKDM4EGFERKMT2ARXFP1
SCHEMBL29908977 0.76 PPM1B (0.79) PPM1BKDM4EGFERKMT2ARXFP1
SCHEMBL18911215 0.74 CCNC (0.49) PRKCIARHSD11B1FASNCCNC
SCHEMBL20660663 0.74 ALDH1A1 (0.57) PRKCIARHSD11B1LRRK2CYP2A6
SCHEMBL17177763 0.74 PPM1B (0.70) PPM1BKDM4EGFERKMT2ARXFP1
SCHEMBL30314350 0.74 PPM1B (0.70) PPM1BKDM4EGFERKMT2ARXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101412682-B Process for synthesizing aryl anthranilic acid and derivatives thereof SHANGHAI PHARMATECH CO LTD 2012-06-27 CN disclosed
CN-101412682-A Process for synthesizing aryl anthranilic acid and derivatives thereof SHANGHAI PHARMATECH CO LTD (CN) 2009-04-22 CN disclosed