Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.37 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16711902 | 0.80 | KCNH2 (0.43) | ALDH1A1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL28071287 | 0.77 | RXRA (0.49) | ALDH1A1KDM4ELMNANPC1MAPK1 | |
| SCHEMBL16712132 | 0.77 | KCNH2 (0.39) | ALDH1A1MEN1MAPTKMT2AACLY | |
| SCHEMBL4302034 | 0.76 | KCNN4 (0.52) | ALDH1A1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL30038214 | 0.76 | KCNN4 (0.52) | ALDH1A1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL24214955 | 0.73 | MAPT (0.46) | ALDH1A1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL7031585 | 0.73 | ALDH1A1 (0.46) | ALDH1A1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL31710093 | 0.73 | ALDH1A1 (0.55) | ALDH1A1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL7031591 | 0.73 | ALDH1A1 (0.46) | ALDH1A1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL30719692 | 0.73 | NOTUM (0.53) | ALDH1A1MEN1MAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101420941-A | Use of GPR119 receptor agonists for increasing bone mass and for treating osteoporosis, and related combination therapies | ARENA PHARM INC (US) | 2009-04-29 | — | — | CN | disclosed |