Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYBB | P04839 | 1/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | NOX5 | Q96PH1 | 1/20 | 0.33 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.33 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30118299 | 0.75 | NOS2 (0.43) | NOS2ALOX15HSD17B10JAK2GAA | |
| Dihydrophenanthridine SCHEMBL2087461 | 0.71 | CA12 (0.56) | NOS2ALOX15HSD17B10JAK2GAA | |
| SCHEMBL30555345 | 0.71 | NOS2 (0.41) | NOS2ALOX15HSD17B10JAK2GAA | |
| SCHEMBL4743689 | 0.71 | ALDH1A1 (0.41) | NOS2ALOX15HSD17B10JAK2GAA | |
| SCHEMBL1130729 | 0.71 | NOS2 (0.41) | NOS2ALOX15HSD17B10JAK2GAA | |
| SCHEMBL68595 | 0.71 | CA12 (0.45) | NOS2ALOX15HSD17B10JAK2GAA | |
| Dihydrophenanthridine SCHEMBL29791568 | 0.71 | CA12 (0.56) | NOS2ALOX15HSD17B10JAK2GAA | |
| SCHEMBL17099674 | 0.71 | NOS2 (0.37) | NOS2ALOX15HSD17B10JAK2GAA | |
| Hydrochloric Acid SCHEMBL10863156 | 0.70 | CA12 (0.43) | NOS2ALOX15HSD17B10JAK2GAA | |
| SCHEMBL27425414 | 0.70 | CA12 (0.54) | NOS2ALOX15HSD17B10JAK2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114349684-B | Synthetic method of benzo [ c, d ] indole imine derivative | 西南林业大学 | 2023-03-28 | — | — | CN | claimed |
| CN-114716359-B | Preparation method of hydrogenated indole imine diastereoisomer | 广东医科大学 | 2023-01-17 | — | — | CN | claimed |
| CN-114716359-A | Preparation method of hydrogenated indole imine diastereoisomer | 广东医科大学 | 2022-07-08 | — | — | CN | claimed |
| CN-114349684-A | Synthetic method of benzo [ c, d ] indole imine derivative | 西南林业大学 | 2022-04-15 | — | — | CN | claimed |
| US-6835210-B1 | Oxidative color dyes are contacted with electrode system; kits | UNILEVER HOME & PERSONAL CARE USA, A DIVISION OF CONOPCO, INC. | 2004-12-28 | — | — | US | claimed |
| CN-114716359-B | Preparation method of hydrogenated indole imine diastereoisomer | 广东医科大学 | 2023-01-17 | — | — | CN | disclosed |
| CN-114716359-B | Preparation method of hydrogenated indole imine diastereoisomer | 广东医科大学 | 2023-01-17 | — | — | CN | disclosed |
| CN-114716359-B | Preparation method of hydrogenated indole imine diastereoisomer | 广东医科大学 | 2023-01-17 | — | — | CN | disclosed |
| CN-114716359-A | Preparation method of hydrogenated indole imine diastereoisomer | 广东医科大学 | 2022-07-08 | — | — | CN | disclosed |
| CN-114716359-A | Preparation method of hydrogenated indole imine diastereoisomer | 广东医科大学 | 2022-07-08 | — | — | CN | disclosed |
| CN-114716359-A | Preparation method of hydrogenated indole imine diastereoisomer | 广东医科大学 | 2022-07-08 | — | — | CN | disclosed |
| CN-112979648-A | Synthesis method of gamma-carboline derivative | 江汉大学 | 2021-06-18 | — | — | CN | disclosed |
| US-5087562-A | Treatment of hypercalcemia of malignancy, osteoporosis, and hyperparathyrodism | MERCK & CO., INC. (US) | 1992-02-11 | — | — | US | disclosed |
| US-5087561-A | For bioassay or therapy | MERCK & CO., INC. (US) | 1992-02-11 | — | — | US | disclosed |
| US-4968669-A | HYPERCALCEMIA | MERCK & CO., INC. (US) | 1990-11-06 | — | — | US | disclosed |
| EP-0341963-A2 | Parathyroid hormone antagonists | MERCK & CO. INC. (US) | 1989-11-15 | — | — | EP | disclosed |
| EP-0341962-A2 | Humoral hypercalcemic factor antagonists | MERCK & CO. INC. (US) | 1989-11-15 | — | — | EP | disclosed |
| EP-0293158-A2 | Parathyroid hormone antagonists | MERCK & CO. INC. (US) | 1988-11-30 | — | — | EP | disclosed |
| EP-0293159-A2 | Parathyroid hormone antagonists with simplified synthetic methodology | MERCK & CO. INC. (US) | 1988-11-30 | — | — | EP | disclosed |
| US-4771124-A | Parathyroid hormone antagonists with simplified synthetic methodology | MERCK & CO., INC. (US) | 1988-09-13 | — | — | US | disclosed |