Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | CYBB | P04839 | 1/20 | 0.30 |
| ▸ | GPR3 | P46089 | 1/20 | 0.30 |
| ▸ | NOX5 | Q96PH1 | 1/20 | 0.30 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.30 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1376468 | 0.79 | NOS2 (0.37) | NOS2ALOX15HSD17B10JAK2GAA | |
| SCHEMBL2776950 | 0.71 | NOS2 (0.41) | NOS2ALOX15HSD17B10JAK2GAA | |
| SCHEMBL30555345 | 0.71 | NOS2 (0.41) | NOS2ALOX15HSD17B10JAK2GAA | |
| SCHEMBL1130729 | 0.71 | NOS2 (0.41) | NOS2ALOX15HSD17B10JAK2GAA | |
| SCHEMBL30118299 | 0.70 | NOS2 (0.43) | NOS2ALOX15HSD17B10JAK2GAA | |
| Ethyne SCHEMBL28619780 | 0.68 | NOS2 (0.38) | NOS2ALOX15HSD17B10JAK2GAA | |
| SCHEMBL68595 | 0.67 | CA12 (0.45) | NOS2ALOX15HSD17B10JAK2GAA | |
| SCHEMBL4743689 | 0.67 | ALDH1A1 (0.41) | NOS2ALOX15HSD17B10JAK2GAA | |
| Dihydrophenanthridine SCHEMBL29791568 | 0.67 | CA12 (0.56) | NOS2ALOX15HSD17B10JAK2GAA | |
| Dihydrophenanthridine SCHEMBL2087461 | 0.67 | CA12 (0.56) | NOS2ALOX15HSD17B10JAK2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11370878-B2 | Systems and methods for production of artificial eumelanin | THE BOARD OF REGENTS FOR OKLAHOMA STATE UNIVERSITY (US) | 2022-06-28 | — | — | US | disclosed |
| US-20200407490-A1 | SYSTEMS AND METHODS FOR PRODUCTION OF ARTIFICIAL EUMELANIN | THE BOARD OF REGENTS FOR OKLAHOMA STATE UNIVERSITY | 2020-12-31 | — | — | US | disclosed |
| US-10774175-B2 | Systems and methods for production of artificial eumelanin | THE BOARD OF REGENTS FOR OKLAHOMA STATE UNIVERSITY (US) | 2020-09-15 | — | — | US | disclosed |
| US-20200031988-A1 | SYSTEMS AND METHODS FOR PRODUCTION OF ARTIFICIAL EUMELANIN | THE BOARD OF REGENTS FOR OKLAHOMA STATE UNIVERSITY | 2020-01-30 | — | — | US | disclosed |
| US-20170174825-A1 | SYSTEMS AND METHODS FOR PRODUCTION OF ARTIFICIAL EUMELANIN | THE BOARD OF REGENTS FOR OKLAHOMA STATE UNIVERSITY | 2017-06-22 | — | — | US | disclosed |
| WO-2015143020-A1 | SYSTEMS AND METHODS FOR PRODUCTION OF ARTIFICIAL EUMELANIN | THE BOARD OF REGENTS FOR OKLAHOMA STATE UNIVERSITY (US) | 2015-09-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170174825-A1 | SYSTEMS AND METHODS FOR PRODUCTION OF ARTIFICIAL EUMELANIN | TYR, COMT, VARS1 | NOS2 1676/4885ALOX15 1113/4885HSD17B10 2925/4885 |
| US-20200031988-A1 | SYSTEMS AND METHODS FOR PRODUCTION OF ARTIFICIAL EUMELANIN | TYR, COMT, VARS1 | NOS2 1676/4885ALOX15 1113/4885HSD17B10 2925/4885 |
| US-10774175-B2 | Systems and methods for production of artificial eumelanin | TYR, COMT, VARS1 | NOS2 1676/4885ALOX15 1113/4885HSD17B10 2925/4885 |
| US-11370878-B2 | Systems and methods for production of artificial eumelanin | TYR, COMT, VARS1 | NOS2 1676/4885ALOX15 1113/4885HSD17B10 2925/4885 |
| US-20200407490-A1 | SYSTEMS AND METHODS FOR PRODUCTION OF ARTIFICIAL EUMELANIN | TYR, COMT, VARS1 | NOS2 1676/4885ALOX15 1113/4885HSD17B10 2925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.