Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Phthalic Anhydride. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.41 |
| ▸ | ACSL1 | P33121 | 2/20 | 0.40 |
| ▸ | ACSL6 | Q9UKU0 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalic Anhydride SCHEMBL28952608 | 0.98 | ALOX15 (0.44) | ALOX15TDP1FFAR4ACSL1ACSL6 | |
| Nonanoate SCHEMBL11749939 | 0.90 | CDC25A (0.46) | ALOX15TDP1FFAR4PPARAHDAC11 | |
| Phthalic Anhydride SCHEMBL28942215 | 0.89 | FFAR4 (0.38) | ALOX15TDP1FFAR4ACSL1ACSL6 | |
| Phthalic Anhydride SCHEMBL28323891 | 0.87 | ALOX15 (0.56) | ALOX15TDP1ALDH1A1MAPK1 | |
| Phthalic Anhydride SCHEMBL185274 | 0.85 | ALOX15 (0.58) | ALOX15TDP1ALDH1A1MAPK1 | |
| Phthalic Anhydride SCHEMBL6437106 | 0.85 | ALOX15 (0.58) | ALOX15TDP1HDAC3HDAC4HDAC1 | |
| Phthalic Anhydride SCHEMBL28312849 | 0.84 | ALOX15 (0.56) | ALOX15TDP1HDAC3HDAC4HDAC1 | |
| Sebacic Acid SCHEMBL4451750 | 0.84 | TDP1 (0.56) | ALOX15TDP1HDAC3HDAC4HDAC1 | |
| Phthalic Acid SCHEMBL28414620 | 0.80 | ALDH1A1 (0.47) | ALOX15FFAR4PPARAHDAC3HDAC4 | |
| Phthalic Anhydride SCHEMBL5943047 | 0.79 | ALOX15 (0.50) | ALOX15TDP1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101628963-B | Bicomponent for manufacturing polyester polyurethane woodlike material | XUCHUAN CHEMICAL SUZHOU CO LTD | 2011-04-13 | — | — | CN | disclosed |
| CN-101628963-A | Bicomponent for manufacturing polyester polyurethane woodlike material | TAICANG XUCHUAN RESIN CO LTD | 2010-01-20 | — | — | CN | disclosed |