Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 4/20 | 0.80 |
| ▸ | MMP2 | P08253 | 4/20 | 0.80 |
| ▸ | MMP9 | P14780 | 4/20 | 0.80 |
| ▸ | EGFR | P00533 | 2/20 | 0.80 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31067997 | 0.88 | RAB9A (0.66) | MMP1MMP2MMP9EGFRTRPV1 | |
| SCHEMBL7663681 | 0.86 | MMP1 (0.72) | MMP1MMP2MMP9EGFRTRPV1 | |
| SCHEMBL13675885 | 0.84 | TRPV1 (1.00) | MMP1MMP2MMP9EGFRTRPV1 | |
| SCHEMBL296725 | 0.84 | SMN1; SMN2 (0.77) | MMP1MMP2MMP9EGFRTRPV1 | |
| SCHEMBL31067969 | 0.83 | NPC1 (0.60) | MMP1MMP2MMP9EGFRTRPV1 | |
| SCHEMBL6786949 | 0.83 | TRPA1 (0.74) | MMP1MMP2MMP9ALDH1A1KDM4E | |
| SCHEMBL6786952 | 0.83 | TRPA1 (0.74) | MMP1MMP2MMP9ALDH1A1KDM4E | |
| SCHEMBL20538436 | 0.81 | KDM4E (0.63) | MMP1MMP2MMP9EGFRALDH1A1 | |
| SCHEMBL24641305 | 0.81 | MMP1 (0.82) | MMP1MMP2MMP9EGFRALDH1A1 | |
| SCHEMBL20537564 | 0.80 | ALDH1A1 (0.60) | ALDH1A1KDM4EHPGDSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101490006-A | Biaryl carboxylic acid arylamides as vanilloid-1 receptor modulators | PHARMESTE SRL (IT) | 2009-07-22 | — | — | CN | disclosed |