Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 4/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16462683 | 0.81 | GAA (0.53) | GAAMAPTRAD52GFERHTR7 | |
| SCHEMBL1815031 | 0.78 | DRD2 (0.46) | MAPTADRA1BADRA1DADRA1AHTT | |
| SCHEMBL1811703 | 0.77 | OPRL1 (0.38) | — | |
| SCHEMBL188362 | 0.76 | ADRA2C (0.42) | GAAMAPTRAD52GFERLMNA | |
| SCHEMBL2033939 | 0.76 | ALDH1A1 (0.46) | GAAMAPTHTTATMPOLB | |
| SCHEMBL27874600 | 0.75 | GAA (0.38) | GAAMAPTRAD52GFERHTR7 | |
| SCHEMBL16462696 | 0.75 | BRD1 (0.39) | GAAMAPTRAD52GFERHTR7 | |
| SCHEMBL17838720 | 0.75 | SIGMAR1 (0.51) | LMNAATMPOLB | |
| SCHEMBL188346 | 0.75 | HTR2A (0.39) | HTR7ADRA1BADRA1DADRA1AHTR1A | |
| SCHEMBL27770419 | 0.74 | CHRNA7 (0.38) | GAAMAPTRAD52GFERHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101432284-A | Dihydropyrazolopyrimidinone derivative | BANYU PHARMA CO LTD (JP) | 2009-05-13 | — | — | CN | disclosed |