Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 2/20 | 0.35 |
| ▸ | GOPC | Q9HD26 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28081439 | 0.77 | PTGER4 (0.33) | CFTRGOPCALDH1A1LMNAMAPT | |
| SCHEMBL27575468 | 0.71 | CFTR (0.35) | CFTRGOPCALDH1A1CYP2A6LMNA | |
| SCHEMBL16857693 | 0.70 | ALDH1A1 (0.40) | CFTRGOPCALDH1A1 | |
| SCHEMBL1673336 | 0.70 | ALDH1A1 (0.40) | CFTRGOPCALDH1A1 | |
| SCHEMBL17421924 | 0.67 | ALDH1A1 (0.36) | CFTRGOPCALDH1A1CHRM2CHRM4 | |
| SCHEMBL28018656 | 0.67 | CALM1 (0.39) | ALDH1A1CYP2A6LMNA | |
| SCHEMBL27770528 | 0.67 | CFTR (0.35) | CFTRGOPCALDH1A1LMNAMAPT | |
| SCHEMBL2792098 | 0.66 | — | — | |
| SCHEMBL8516623 | 0.65 | CFTR (0.50) | CFTRGOPCALDH1A1CYP2A6LMNA | |
| SCHEMBL5240697 | 0.64 | SIGMAR1 (0.37) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101489555-A | Nf-kappa | OTSUKA PHARMA CO LTD (JP) | 2009-07-22 | — | — | CN | disclosed |