Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18866771 | 0.78 | HTR2C (0.51) | HTR2C | |
| Biphenyl SCHEMBL8985997 | 0.74 | ALDH1A1 (0.45) | ALDH1A1LMNA | |
| SCHEMBL17993740 | 0.72 | SIGMAR1 (0.39) | SIGMAR1HTR2CESR2SLC18A3 | |
| SCHEMBL14336758 | 0.72 | PLAU (0.41) | SIGMAR1HTR2CESR2SLC18A3 | |
| SCHEMBL10930465 | 0.72 | SIGMAR1 (0.39) | SIGMAR1HTR2CESR2SLC18A3 | |
| SCHEMBL14336997 | 0.72 | MAT2A (0.45) | SIGMAR1HTR2CESR2ALDH1A1SLC18A3 | |
| SCHEMBL5239393 | 0.72 | MAT2A (0.45) | SIGMAR1HTR2CESR2ALDH1A1SLC18A3 | |
| SCHEMBL19746393 | 0.72 | NPC1 (0.46) | ESR2ALDH1A1LMNAGAA | |
| Biphenyl SCHEMBL958819 | 0.69 | G6PC1 (0.40) | ALDH1A1LMNA | |
| Biphenyl SCHEMBL28165827 | 0.69 | G6PC1 (0.40) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263735-B1 | ACID ADDITION SALTS OF IMIDAZOLIDINONES AS REACTION CATALYSTS | UNIV CALIFORNIA (US) | 2007-07-04 | — | — | EP | disclosed |
| US-6534434-B2 | Catalyst for unsaturated carbonyl compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-03-18 | — | — | US | disclosed |
| US-6515137-B2 | Enantioselectivity of alpha,beta-unsaturated aldehydes | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-02-04 | — | — | US | disclosed |
| US-6369243-B1 | ACID CATALYST | THE REGENTS OF THE UNIVERISITY OF CALIFORNIA | 2002-04-09 | — | — | US | disclosed |
| US-20020016473-A1 | Catalytic processes employing chiral imidazolidinone-based catalyst composition | MACMILLAN DAVID W C (US) | 2002-02-07 | — | — | US | disclosed |
| US-20020013475-A1 | Chiral imidazolidinone-based catalyst composition and reaction system | MACMILLAN DAVID W C (US) | 2002-01-31 | — | — | US | disclosed |
| US-6307057-B1 | CATALYZE ENANTIOSELECTIVE REACTIONS, E.G., DIELS-ALDER REACTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2001-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020013475-A1 | Chiral imidazolidinone-based catalyst composition and reaction system | COASY, DHPS, INTS9 | SIGMAR1 2455/4885HTR2C 3081/4885ESR2 1825/4885 |
| US-20020016473-A1 | Catalytic processes employing chiral imidazolidinone-based catalyst composition | COASY, ALDH3A1, TALDO1 | SIGMAR1 2493/4885HTR2C 4113/4885ESR2 2246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.