SCHEMBL27770592

SCHEMBL27770592

C[Si](C)(C)c1ccc([SiH3])cc1

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.41
NR1H3 Q13133 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL586534 0.83 NR1H2 (0.50) NR1H2NR1H3
SCHEMBL10997473 0.73 NR1H2 (0.44) NR1H2NR1H3
SCHEMBL987122 0.71 ACHE (0.53) NR1H2NR1H3
SCHEMBL8099751 0.71
SCHEMBL6124152 0.71 TYR (0.42) NR1H2NR1H3
SCHEMBL19225097 0.71 NR1H2 (0.38) NR1H2NR1H3
SCHEMBL8307844 0.69 NR1H2 (0.37) NR1H2NR1H3
SCHEMBL23612702 0.69 NR1H2 (0.48) NR1H2NR1H3
SCHEMBL570229 0.69 CYP2A6 (0.50) NR1H2NR1H3
SCHEMBL6512153 0.69 NR1H2 (0.41) NR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114874244-B Preparation method of aryl borate or alkyl borate compound 中国科学院兰州化学物理研究所 2023-12-01 CN disclosed
CN-114874244-A Preparation method of arylboronic acid ester or alkyl boronate compound 中国科学院兰州化学物理研究所 2022-08-09 CN disclosed
CN-101910202-B Biocompatible three dimensional matrix for immobilization of biological substances 白血球保健股份有限公司 2016-11-09 CN disclosed
CN-103459405-B Process for producing transition metal complex, catalyst for trimerization, process for producing 1-hexene, process for producing substituted cyclopentadiene compound (1) 住友化学株式会社 2016-09-28 CN disclosed
CN-103459406-B For the preparation of the method for transition metal complex, for the catalyzer of trimerization, for the preparation of the method for 1-hexene, for the preparation of the method (2) of the cyclopentadiene compound replaced SUMITOMO CHEMICAL CO.,LTD. (JP) 2016-03-16 CN disclosed
CN-102666561-B Transition metal complex, the cyclopentadiene compound of catalyst for trimerization and replacement SUMITOMO CHEMICAL CO.,LTD. (JP) 2015-11-25 CN disclosed
CN-103459405-A Process for producing transition metal complex, catalyst for trimerization, process for producing 1-hexene, process for producing substituted cyclopentadiene compound SUMITOMO CHEMICAL CO 2013-12-18 CN disclosed
CN-103459406-A Method for producing the transition metal complex, catalyst for trimerization, method for producing 1-hexene, method for producing the substituted cyclopentadiene compound (2) SUMITOMO CHEMICAL CO 2013-12-18 CN disclosed
CN-102666561-A Transition metal complex, preparation method for said transition metal complex, trimerization catalyst, preparation method for 1-hexene, preparation method for ethylene polymer, substituted cyclopentadiene compound, and preparation method for said su SUMITOMO CHEMICAL CO 2012-09-12 CN disclosed
CN-101437853-B Biocompatible three dimensional matrix for the immobilization of biological substances LEUKOCARE AG 2012-07-04 CN disclosed
CN-101910202-A Biocompatible three dimensional matrix for the immobilization of biological substances LEUKOCARE AG 2010-12-08 CN disclosed
CN-101437853-A Biocompatible three dimensional matrix for the immobilization of biological substances LEUKOCARE AG (DE) 2009-05-20 CN disclosed