Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FADS1 | O60427 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 4/20 | 0.53 |
| ▸ | MAOA | P21397 | 3/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.50 |
| ▸ | PNLIP | P16233 | 1/20 | 0.50 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13812595 | 0.88 | P2RX1 (0.60) | FADS1P2RX1MAOBMAOANR1H4 | |
| SCHEMBL27771260 | 0.87 | FADS1 (0.52) | FADS1MEN1KMT2AMAOBMAOA | |
| SCHEMBL27771283 | 0.84 | FADS1 (0.67) | FADS1P2RX1MAOBMAOANPC1 | |
| SCHEMBL13812651 | 0.82 | P2RX1 (0.62) | FADS1P2RX1NR1H4TMPRSS4 | |
| SCHEMBL27792367 | 0.81 | MEN1 (0.60) | MEN1KMT2AMAOBMAOAALDH1A1 | |
| SCHEMBL24438058 | 0.81 | TMPRSS4 (0.67) | P2RX1ALDH1A1NPC1MAPTPKM | |
| SCHEMBL13812610 | 0.79 | P2RX1 (0.61) | FADS1MEN1KMT2AP2RX1MAOB | |
| SCHEMBL13812903 | 0.79 | KCNMA1 (0.55) | MEN1KMT2AP2RX1ALDH1A1NPC1 | |
| SCHEMBL13812602 | 0.78 | P2RX1 (0.58) | FADS1P2RX1NR1H4MAPTTMPRSS4 | |
| SCHEMBL13812611 | 0.78 | P2RX1 (0.66) | FADS1MEN1KMT2AP2RX1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101648919-A | 3-substituted salicylamide compound, preparation method, medicinal composition and application thereof | INST MATERIA MEDICA CAMS | 2010-02-17 | — | — | CN | disclosed |