Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FADS1 | O60427 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 6/20 | 0.50 |
| ▸ | MAOA | P21397 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.50 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.49 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.43 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27771246 | 0.87 | FADS1 (0.57) | FADS1MAOBMAOAKDM4ENPC1 | |
| SCHEMBL27792361 | 0.84 | KCNMA1 (0.66) | FADS1MAOBMAOAKDM4EKCNMA1 | |
| SCHEMBL13812595 | 0.82 | P2RX1 (0.60) | FADS1MAOBMAOANR1H4SPHK2 | |
| SCHEMBL14156888 | 0.78 | KDM4E (0.57) | MAOBKDM4EPRMT5NR3C2RAB9A | |
| SCHEMBL27771283 | 0.77 | FADS1 (0.67) | FADS1MAOBMAOANPC1RAB9A | |
| SCHEMBL13812903 | 0.76 | KCNMA1 (0.55) | KDM4EKCNMA1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28784923 | 0.76 | MAOB (0.46) | FADS1MAOBMAOA | |
| SCHEMBL27771252 | 0.76 | KCNMA1 (0.65) | FADS1MAOBMAOAKCNMA1NPC1 | |
| SCHEMBL27771238 | 0.75 | MAOB (0.54) | MAOBMAOAKDM4ENPC1RAB9A | |
| SCHEMBL13812651 | 0.75 | P2RX1 (0.62) | FADS1KCNMA1NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101648919-A | 3-substituted salicylamide compound, preparation method, medicinal composition and application thereof | INST MATERIA MEDICA CAMS | 2010-02-17 | — | — | CN | disclosed |