Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MET | P08581 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27771246 | 0.81 | FADS1 (0.57) | MEN1KMT2AALDH1A1MAPTMAOB | |
| SCHEMBL12173161 | 0.77 | MEN1 (0.53) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL27792404 | 0.77 | MEN1 (0.70) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL27792371 | 0.75 | ALDH1A1 (0.60) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL27936544 | 0.75 | MAPT (0.60) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL27863133 | 0.75 | MAOB (0.67) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL7921889 | 0.74 | MAOB (0.68) | MEN1KMT2AMAOBMAOA | |
| SCHEMBL24696857 | 0.73 | MAOB (0.62) | MEN1KMT2AALDH1A1MAPTMAOB | |
| SCHEMBL27792405 | 0.72 | KMT2A (0.47) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL12173128 | 0.72 | MAPT (0.55) | MEN1KMT2AALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101648919-A | 3-substituted salicylamide compound, preparation method, medicinal composition and application thereof | INST MATERIA MEDICA CAMS | 2010-02-17 | — | — | CN | disclosed |