Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.56 |
| ▸ | LRRK2 | Q5S007 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MET | P08581 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | GCK | P35557 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27792371 | 0.86 | ALDH1A1 (0.60) | SGMS2LRRK2ALDH1A1LMNAMET | |
| SCHEMBL27771292 | 0.80 | SGMS2 (0.52) | SGMS2LRRK2ALDH1A1LMNAMET | |
| SCHEMBL27792413 | 0.76 | NPC1 (0.49) | LRRK2LMNANPC1RAB9AMEN1 | |
| SCHEMBL1647532 | 0.74 | LRRK2 (0.78) | SGMS2LRRK2ALDH1A1LMNAMET | |
| SCHEMBL17551827 | 0.73 | SGMS2 (1.00) | SGMS2LRRK2ALDH1A1LMNAMET | |
| SCHEMBL30322922 | 0.73 | SGMS2 (1.00) | SGMS2LRRK2ALDH1A1LMNAMET | |
| SCHEMBL6930256 | 0.73 | CXCR2 (0.58) | SGMS2ALDH1A1NPC1RAB9AGCK | |
| SCHEMBL29179302 | 0.72 | FOLH1 (0.60) | LRRK2ALDH1A1SMN1; SMN2PTGER1 | |
| SCHEMBL27584561 | 0.71 | GCK (0.54) | SGMS2ALDH1A1LMNAGCKSMN1; SMN2 | |
| SCHEMBL17551776 | 0.71 | SGMS2 (0.78) | SGMS2LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101648919-A | 3-substituted salicylamide compound, preparation method, medicinal composition and application thereof | INST MATERIA MEDICA CAMS | 2010-02-17 | — | — | CN | disclosed |