Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.52 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.49 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.48 |
| ▸ | MET | P08581 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27771254 | 0.80 | SGMS2 (0.56) | SGMS2PTGER1METKMT2AALDH1A1 | |
| SCHEMBL27792486 | 0.78 | MAOB (0.55) | MAOAMAOBKDM4ENPC1RAB9A | |
| SCHEMBL27792371 | 0.76 | ALDH1A1 (0.60) | SGMS2METKMT2AALDH1A1LMNA | |
| SCHEMBL27792464 | 0.75 | KCNMA1 (0.55) | KCNMA1KMT2AALDH1A1LMNAMAOA | |
| SCHEMBL27792361 | 0.75 | KCNMA1 (0.66) | SGMS2KCNMA1METKMT2AALDH1A1 | |
| SCHEMBL710194 | 0.74 | MAOB (0.57) | KMT2AALDH1A1LMNAMAOBMEN1 | |
| SCHEMBL1647532 | 0.70 | LRRK2 (0.78) | SGMS2METALDH1A1LMNALRRK2 | |
| SCHEMBL11720308 | 0.70 | KDM4E (0.64) | SGMS2KMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL17551827 | 0.69 | SGMS2 (1.00) | SGMS2METKMT2AALDH1A1LMNA | |
| SCHEMBL30322922 | 0.69 | SGMS2 (1.00) | SGMS2METKMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101648919-A | 3-substituted salicylamide compound, preparation method, medicinal composition and application thereof | INST MATERIA MEDICA CAMS | 2010-02-17 | — | — | CN | claimed |
| CN-101648919-A | 3-substituted salicylamide compound, preparation method, medicinal composition and application thereof | INST MATERIA MEDICA CAMS | 2010-02-17 | — | — | CN | disclosed |