Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | PPIA | P62937 | 1/20 | 0.45 |
| ▸ | MET | P08581 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27771254 | 0.86 | SGMS2 (0.56) | ALDH1A1LMNAMEN1KMT2ASGMS2 | |
| SCHEMBL28784924 | 0.83 | ALDH1A1 (0.53) | ALDH1A1LMNAMEN1KMT2ASGMS2 | |
| SCHEMBL27771256 | 0.79 | MAPT (0.50) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL27771292 | 0.76 | SGMS2 (0.52) | ALDH1A1LMNAMEN1KMT2ASGMS2 | |
| SCHEMBL27792405 | 0.76 | KMT2A (0.47) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL27792367 | 0.75 | MEN1 (0.60) | ALDH1A1LMNAMEN1KMT2ALRRK2 | |
| SCHEMBL17551780 | 0.72 | MEN1 (0.79) | ALDH1A1MEN1KMT2ASGMS2LRRK2 | |
| SCHEMBL27792404 | 0.71 | MEN1 (0.70) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL15855145 | 0.71 | ALDH1A1 (0.58) | ALDH1A1LMNAMEN1KMT2ATP53 | |
| SCHEMBL1647532 | 0.71 | LRRK2 (0.78) | ALDH1A1LMNASGMS2LRRK2MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101648919-A | 3-substituted salicylamide compound, preparation method, medicinal composition and application thereof | INST MATERIA MEDICA CAMS | 2010-02-17 | — | — | CN | disclosed |