Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 7/20 | 0.53 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25600275 | 0.84 | LMNA (0.49) | HSD11B1PSIP1LMNAMAPTKDM4E | |
| SCHEMBL156165 | 0.84 | HSD11B1 (0.55) | HSD11B1PSIP1LMNAMAPTL3MBTL1 | |
| SCHEMBL27505035 | 0.84 | KMT2A (0.48) | HSD11B1LMNAKDM4EL3MBTL1 | |
| SCHEMBL9394874 | 0.84 | MAPT (0.47) | HSD11B1PSIP1LMNAMAPTKDM4E | |
| SCHEMBL11407383 | 0.83 | HSD11B1 (0.56) | HSD11B1PSIP1LMNAMAPTL3MBTL1 | |
| SCHEMBL12237322 | 0.83 | CA2 (0.53) | HSD11B1PSIP1LMNAMAPTL3MBTL1 | |
| SCHEMBL111775 | 0.82 | HSD11B1 (0.53) | HSD11B1PSIP1LMNAMAPTL3MBTL1 | |
| SCHEMBL10894318 | 0.82 | TSHR (0.45) | HSD11B1LMNAKDM4E | |
| SCHEMBL27488716 | 0.81 | MMP1 (0.63) | LMNAL3MBTL1SMN1; SMN2HTT | |
| SCHEMBL7523793 | 0.81 | HSD11B1 (0.51) | HSD11B1PSIP1LMNAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103509135-B | Olefin polymerization catalyst component, preparation method and application thereof | CHINA PETROLEUM & CHEMICAL | 2015-07-22 | — | — | CN | disclosed |
| CN-103509135-A | Olefin polymerization catalyst component, preparation method and application thereof | CHINA PETROLEUM & CHEMICAL | 2014-01-15 | — | — | CN | disclosed |
| CN-101987835-A | Homopiperazine acethydrazide derivatives | SHENZHEN INST OF XIANGYA BIOMEDICINE | 2011-03-23 | — | — | CN | disclosed |
| CN-101503394-B | High piperazine acetydrazide derivatives, and preparation and use thereof | SHENZHEN XIANGYA BIOLOGY MEDICAMENT ACADEMY | 2010-05-12 | — | — | CN | disclosed |
| CN-101503394-A | High piperazine acetydrazide derivatives, and preparation and use thereof | SHENZHEN XIANGYA BIOLOGY MEDIC (CN) | 2009-08-12 | — | — | CN | disclosed |